Testing Tool for Animals
Currently
the vast majority of antibodies available for research purpose produced by live
animals through procedures that are of great concern from both animal’s welfare
and scientific stand point. Millions of animals suffer for prolonged periods of
time to produce antibodies used in research.
Two methods
are used to produce the two types of antibodies that are most commonly used in research:
Monoclonal Antibodies and Polyclonal Antibodies. In the mouse monoclonal as
cites methods, once the animals begins making the desired antibody, the mice
are killed and their spleens are harvested to isolate the antibodies produced B
lymphocyte.
These cells are then fused with
cancerous cells to generate a hybridoma which will multiply indefinitely. These
hybridomas are injected into the abdominal cavities of mine where they multiply
continually.
Achievements:
Research with cows helped create the
world’s first vaccine, which in turn helped end small pox. Studies with
monkeys, dogs and mice led to the polio vaccine.
Animal
testing is not an alternative to human trials, it complements it. Thus we
cannot completely rely on the animal testing and take it for granted that they
will surpass the human testing phases as well. To have the discussions about
the clinical trials and animal testing please join the forum of Clinical Research and Biomarkers (WCCRB-2018) which is
during September 17-18, 2018 at Toronto, Canada.
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