Biomarkers in the Health and Depression Disorder

Biomarkers are used in all health fields to aid in the diagnosis of illnesses. By definition, biomarkers are a measurable substance that is an indicator of a distinct disease, infection, or environmental exposure.  Biomarkers include ions, genetic markers, proteins, and structural abnormalities. Mental health scientists are currently working on many different biomarkers in order to help define, identify, and effectively treat mental illnesses. A biomarker in mental health is blood testing and urine sampling, which is now being used to detect disorders such as Alzheimer’s disease and Major Depressive Disorder.

The next most common form of depression is Low-Folate depression folate is one of the B-vitamins. Folaters’ primary job is to convert B12 Vitamin into a different form so it can be used in DNA synthesis. Foliate is also involved in cell growth. There is a specific form of folate that has access to the brain. This specific kind of Folate, known as Methylfolate, and it is involved in the synthesis of Serotonin as well as other neurotransmitters.  By administering this Folate to individuals suffering from depression, it will create more Serotonin in the brain and ultimately aid in alleviating symptoms.

Biomarkers of treatment response may enable clinicians to target the appropriate drug for each patient. Biomarkers need to have accuracy in real life, sensitivity, specificity, and relevance to depression. Introduction of Depressive Disorder biomarkers into the health care system can increase the overall cost of clinical diagnosis of patients. Because of that, decisions to allocate health research funding must be based on drug effectiveness and cost-effectiveness. The assessment of Depressive Disorder biomarkers should include reliable evidence of associated drug effectiveness, adverse events and consequences. To have the discussions about the Biomarkers in the health and depression disorder of Clinical Research and Biomarkers (WCCRB-2018) this is during September 17-18, 2018 at Toronto, Canada

Link : http://scientificfederation.com/clinical-research-2018/