Traditional
methods for assessing dietary exposure can be unreliable, with under reporting
one of the main problems. In an attempt to overcome such problems there is
increasing interest in identifying biomarkers of dietary intake to provide a
more accurate measurement. Metabolomics is an analytical technique that aims to
identify and quantify small metabolites. Recently, there has been an increased
interest in the application of metabolomics coupled with statistical analysis
for the identification of dietary biomarkers, with a number of putative
biomarkers identified. Dietary biomarkers rule out this problem, and highlight
that dietary suggestions to avoid red meat and saturated fat and increase uptake of plant-based oils and whole grains seems to hold it true, at least in
this group of women.
Diet
is an important factor assessing point in developing type 2 diabetes whole
grains, vegetable oils and good vitamin E status found to be primary aspects
against type 2 diabetes, whereas saturated fat and meat increased the chances
for developing the disease. It was very fortunate that researchers were able to
reach these conclusions without having any additional data on diet through the
subjects.
Down the line blood samples were collected,
where a unique metabolic fingerprint, including many different diet biomarkers,
could be linked to each woman at the specific time the sample was taken. Using
this method it was possible for the first time to objectively determine the
impact of key dietary components on future type 2 diabetes risks, as well as to
compare the dietary patterns between women having and without having type 2
diabetes. The new method has allowed scientists to measure several markers of
diet and nutrient status at the same time in a large number of people, which
they believed is the pioneering one in this area.
The
role of diet is generally discussed as a preventative strategy for developing
type 2 diabetes, this new research provides strong evidence for dietary
guidelines, and underlines the significance of changing diet to improve health.
Collecting information about diet can be complicated and time consuming, and is
always biased by what people remember and think they should report. New methods
such as this shall contribute to recover how we measure diet and understand in
more detail how dietary patterns relate to disease.
To have more information about the dietary biomarkers please
join our conference.
Clinical Research and Biomarkers (WCCRB-2018)
which is during September 17-18, 2018 at Toronto, Canada